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Moreover, internal triggers like excess sugar, processed foods, trans fats, and hormonal dysregulation (like insulin resistance or PCOS) can worsen acne and delay wound healing

At the same time, combined with metabolomics, 16S rRNA sequencing and MetOrigin, the compatibility mechanism of XJZ in the treatment of CAG was explored from the changes in intestinal microbiota and metabolites

During healing, melanin production increases, often leaving post-inflammatory hyperpigmentation (PIH)

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Ethics statement The studies involving human participants were reviewed and approved by CAMH Research Ethics Board